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Longevity

Elamipretide

Also called SS-31, Forzinity, MTP-131, Bendavia

InjectableEvidence AEvery day
Half-life
2hours
Typical vial
40mg
Research amounts
40–40mg

per administration

Common schedule
Every day
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Licensed as a medicine in the US.

Quick start

Elamipretide at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.

Typical dose
40–40 mg per administration
How often
Every day
Where
Subcutaneous — abdomen, thigh, or upper arm Sites and rotation
Time to steady level
~10 hours — about five half-lives
Storage
Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details

A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.

Work out your draw

These numbers are a starting point — change any of them.

Vial label

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Published research contexts for Elamipretide describe 4040 mg per administration. Descriptive only, not a recommendation.

A mitochondrial-targeted (Szeto–Schiller) peptide that binds cardiolipin on the inner mitochondrial membrane; studied at 40 mg daily subcutaneously and licensed as a medicine in the US in 2025 under the brand Forzinity.

Dosing schedule

How Elamipretide is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
MaintenanceThe single daily amount used in the TAZPOWER trial and carried onto the Forzinity label; no escalation was reported.40 mgOnce dailySubQ

Modelled level — every day

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
10hours

About five half-lives

Administrations
7/ week

Where these numbers come from

  • TAZPOWER (Reid Thompson W et al., Genetics in Medicine 2021)Randomized crossover then open-label extension of elamipretide 40 mg/day subcutaneously in Barth syndrome trial participants.
  • Forzinity (elamipretide) product labelBrand approved in the US in 2025; 40 mg once-daily subcutaneous dosing.

Next steps

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