Metabolic
Exenatide
Also called Byetta, Bydureon, Exendin-4
per administration
A human trial worked out how much to take and how often, so a dosing schedule is shown.
Licensed as a medicine in the US and EU.
Quick start
Exenatide at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.
- Typical dose
- 5–10 mcg per administration
- How often
- Twice a day
- Where
- Subcutaneous — abdomen, thigh, or upper arm Sites and rotation
- Time to steady level
- ~12 hours — about five half-lives
- Storage
- Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details
A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.
Key properties
Molecular reference data.
- Formula
- C184H282N50O60S
- Mol. weight
- 4,186.63 Da
- CAS
- 141758-74-9
- PubChem CID
- 16157882
External references
Work out your draw
These numbers are a starting point — change any of them.
Vial label
Copy this into your label printer.
Published research contexts for Exenatide describe 5–10 mcg per administration. Descriptive only, not a recommendation.
About 2.4 hours for the immediate-release form; the separate extended-release depot clears far more slowly.
Dosing schedule
How Exenatide is commonly stepped up, for reference only.
These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.
| Phase | Amount | Frequency | Route |
|---|---|---|---|
| Weeks 1–4Within 60 minutes before the morning and evening meals; conservative start. | 5 mcg | Twice daily | SubQ |
| Week 5+Step up only if the lower amount is tolerated. | 10 mcg | Twice daily | SubQ |
Modelled level — twice a day
1× is the peak after a single dose.
- Steady-state peak
- 1.03× single dose
- Time to steady state
- 12hours
- Administrations
- 14/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- DeFronzo RA et al., Diabetes Care 2005;28:1092A GLP-1 receptor agonist (exendin-4); 5 and 10 mcg twice daily over 30 weeks improved glycaemic measures in adults with type-2 diabetes on metformin.