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Recovery

Glepaglutide

Also called ZP1848

InjectableEvidence AOnce a week
Half-life
50hours
Typical vial
10mg
Research amounts
10–10mg

per administration

Common schedule
Once a week
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Quick start

Glepaglutide at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.

Typical dose
10–10 mg per administration
How often
Once a week
Where
Subcutaneous — abdomen, thigh, or upper arm Sites and rotation
Time to steady level
~10.4 days — about five half-lives
Storage
Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details

A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.

Work out your draw

These numbers are a starting point — change any of them.

Vial label

Copy this into your label printer.

Published research contexts for Glepaglutide describe 1010 mg per administration. Descriptive only, not a recommendation.

Roughly two days from limited reports; the figure is thin and estimates vary.

Dosing schedule

How Glepaglutide is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
Reported doseThe long half-life supports weekly spacing; the EASE program ran 10 mg once or twice weekly.10 mgOnce or twice weeklySubQ

Modelled level — once a week

1× is the peak after a single dose.

Steady-state peak
1.08× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
10.4days

About five half-lives

Administrations
1/ week

Where these numbers come from

  • Naimi RM et al., Lancet Gastroenterology & Hepatology 2019 (EASE-1)Subcutaneous glepaglutide (ZP1848) assessed for intestinal absorption in short-bowel syndrome; the later EASE program used 10 mg once or twice weekly.

Next steps

Others in recovery