Metabolic
Metreleptin
Also called Myalept
per administration
A human trial worked out how much to take and how often, so a dosing schedule is shown.
Licensed as a medicine in the US and EU.
Quick start
Metreleptin at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.
- Typical dose
- 2.5–10 mg per administration
- How often
- Every day
- Where
- Subcutaneous — abdomen, thigh, or upper arm Sites and rotation
- Time to steady level
- ~20 hours — about five half-lives
- Storage
- Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details
A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.
Work out your draw
These numbers are a starting point — change any of them.
Vial label
Copy this into your label printer.
Published research contexts for Metreleptin describe 2.5–10 mg per administration. Descriptive only, not a recommendation.
Roughly 4 hours in plasma, consistent with once-daily administration.
Dosing schedule
How Metreleptin is commonly stepped up, for reference only.
These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.
| Phase | Amount | Frequency | Route |
|---|---|---|---|
| MaintenanceA recombinant leptin analog dosed by body weight; the licensed label titrates within this range. | 2.5–10 mg (weight-based) | Once daily | SubQ |
Modelled level — every day
1× is the peak after a single dose.
- Steady-state peak
- 1.02× single dose
- Time to steady state
- 20hours
- Administrations
- 7/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- Metreleptin (Myalept / Myalepta) label and lipodystrophy studiesLicensed leptin analog given once daily by body weight in generalized and partial lipodystrophy research.