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Sexual and reproductive health

PT-141

Also called Bremelanotide

InjectableEvidence AOnce a week
Half-life
2.7hours
Typical vial
10mg
Research amounts
0.5–2mg

per administration

Common schedule
Once a week
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Licensed as a medicine in the US.

Quick start

PT-141 at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.

Typical dose
0.5–2 mg per administration
How often
Once a week
Where
Subcutaneous — abdomen, thigh, or upper arm Sites and rotation
Time to steady level
~14 hours — about five half-lives
Storage
Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details

A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.

Key properties

Molecular reference data.

Formula
C50H68N14O10
Mol. weight
1,025.2 Da
CAS
189691-06-3
PubChem CID
9941379

Work out your draw

These numbers are a starting point — change any of them.

Vial label

Copy this into your label printer.

Published research contexts for PT-141 describe 0.52 mg per administration. Descriptive only, not a recommendation.

Dosing schedule

How PT-141 is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
As neededA melanocortin agonist used episodically, not on a standing daily schedule. Nausea is dose-limiting.0.5–2 mgUp to once in 24 h, a few hours beforeSubQ

What it can be combined with

How PT-141 is commonly discussed alongside other peptides and drugs.

Educational reference on commonly-discussed combinations, not medical advice. Combining compounds can change how each behaves — read this as a prompt to research, not a clearance.

  • Melanotan-1 (MT-1)Both are melanocortin-receptor agonists, so together they compound the same effects, including nausea.
    Use caution
  • Melanotan-2 (MT-2)Both are melanocortin-receptor agonists, so combining them intensifies shared effects such as nausea and flushing.
    Use caution

Modelled level — once a week

1× is the peak after a single dose.

Steady-state peak
0.96× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
14hours

About five half-lives

Administrations
1/ week

Where these numbers come from

Next steps