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PeptideWiki.bio

Metabolic

PYY3-36

Also called Peptide YY(3-36)

InjectableEvidence AEvery day
Half-life
0.15hours
Typical vial
5 / 10mg
Research amounts
10–50mcg

per administration

Common schedule
Every day
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

The human evidence for PYY3-36 used the intravenous route. The draw worked out here assumes a subcutaneous injection, so the amount is not a direct read-across.

Quick start

PYY3-36 at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.

Typical dose
10–50 mcg per administration
How often
Every day
Where
Intravenous (clinical setting)
Time to steady level
~1 hours — about five half-lives
Storage
Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details

A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.

Work out your draw

These numbers are a starting point — change any of them.

Vial label

Copy this into your label printer.

Published research contexts for PYY3-36 describe 1050 mcg per administration. Descriptive only, not a recommendation.

Roughly 8–10 minutes; the decay chart is largely illustrative here.

A gut hormone and Y2 receptor agonist studied for reduced food intake. The human evidence used intravenous infusion (Batterham, Nature 2002 and NEJM 2003); no subcutaneous schedule is established, so no schedule table is shown.

Modelled level — every day

1× is the peak after a single dose.

Steady-state peak
0.98× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
1hours

About five half-lives

Administrations
7/ week

Where these numbers come from

  • Batterham RL et al., Nature 2002;418:650Intravenous PYY3-36 infusion reduced food intake in a controlled study of volunteers.
  • Batterham RL et al., NEJM 2003;349:941Intravenous infusion lowered energy intake across lean and obese subjects; the route is infusion, not subcutaneous.

Next steps