Growth hormone axis
Sermorelin
Also called GHRH (1-29), GRF (1-29)
per administration
A human trial worked out how much to take and how often, so a dosing schedule is shown.
Licensed as a medicine in the US, though the product was withdrawn from sale in 2008.
Quick start
Sermorelin at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.
- Typical dose
- 100–500 mcg per administration
- How often
- Every day
- Where
- Subcutaneous — abdomen, thigh, or upper arm Sites and rotation
- Timing
- Usually at night and fasted, to align with the body's own growth-hormone release.
- What people report
- Sleep and recovery contexts are discussed over the first weeks.
- Time to steady level
- ~1 hours — about five half-lives
- Storage
- Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details
- Cycle length
- 8–12 weeks
- Break between
- 4 weeks Why
A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.
Key properties
Molecular reference data.
- Formula
- C149H246N44O42S
- Mol. weight
- 3,357.9 Da
- CAS
- 86168-78-7
- PubChem CID
- 16132413
External references
Structure note
A diagram is a reference representation of the named chemical structure. It does not establish the composition, purity, or identity of any particular vial.
Work out your draw
These numbers are a starting point — change any of them.
Vial label
Copy this into your label printer.
Published research contexts for Sermorelin describe 100–500 mcg per administration. Descriptive only, not a recommendation.
Roughly 11-12 minutes in plasma. One of the shortest here, so the curve is a series of spikes rather than an accumulating level.
Dosing schedule
How Sermorelin is commonly stepped up, for reference only.
These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.
| Phase | Amount | Frequency | Route |
|---|---|---|---|
| Typical blockA very short-acting GHRH analog, timed at night to match natural GH release. | 100–500 mcg | Once daily | SubQ, before bed |
What it can be combined with
How Sermorelin is commonly discussed alongside other peptides and drugs.
Educational reference on commonly-discussed combinations, not medical advice. Combining compounds can change how each behaves — read this as a prompt to research, not a clearance.
- CJC-1295 (DAC)Two GHRH analogs on the same receptor — redundant rather than additive.Use caution
- CJC-1295 (no DAC)Two GHRH analogs on the same receptor — redundant rather than additive.Use caution
- TesamorelinBoth are GHRH analogs; combining them duplicates the same signal.Use caution
- IpamorelinGHRP plus a GHRH analog — different receptors, so they work together.Commonly combined
Modelled level — every day
1× is the peak after a single dose.
- Steady-state peak
- 0.98× single dose
- Time to steady state
- 1hours
- Administrations
- 7/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- Sermorelin GH-axis literatureA GHRH(1–29) analog historically used to probe growth-hormone secretion.