Longevity
FOXO4-DRI
Also called FOXO4-D-Retro-Inverso
per administration
Only animal or lab studies exist — no human study has set an amount.
Quick start
FOXO4-DRI at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.
- Typical dose
- 1–5 mg per administration
- How often
- 3x per week
- Where
- Commonly subcutaneous Sites and rotation
- Time to steady level
- ~10 hours — about five half-lives
- Storage
- Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details
A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.
Work out your draw
These numbers are a starting point — change any of them.
Vial label
Copy this into your label printer.
Published research contexts for FOXO4-DRI describe 1–5 mg per administration. Descriptive only, not a recommendation.
A D-retro-inverso peptide built to resist proteases; no human pharmacokinetics is published, so this is an order-of-magnitude guess.
A senolytic peptide that disrupts the FOXO4–p53 interaction to clear senescent cells in animal and cell models; evidence is preclinical, with no human study fixing an amount or schedule, so no schedule table is shown.
Modelled level — 3x per week
1× is the peak after a single dose.
- Steady-state peak
- 1.00× single dose
- Time to steady state
- 10hours
- Administrations
- 3/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- FOXO4-DRI senolytic study (Baar MP et al., Cell 2017)A D-retro-inverso peptide that cleared senescent cells in aged mice; no human dosing exists.