Longevity
GDF-11
Also called Growth Differentiation Factor 11
per administration
Only animal or lab studies exist — no human study has set an amount.
Quick start
GDF-11 at a glance — the figures, plus how it's commonly run. Reference only, not medical advice.
- Typical dose
- 100–300 mcg per administration
- How often
- Every day
- Where
- Commonly subcutaneous Sites and rotation
- Time to steady level
- ~5 hours — about five half-lives
- Storage
- Dry vial kept cold and dark; a mixed vial in the fridge at 2–8 °C. Details
A research and community reference, not medical advice. Figures are descriptive, vary between sources, and are not a recommendation for use.
Work out your draw
These numbers are a starting point — change any of them.
Vial label
Copy this into your label printer.
Published research contexts for GDF-11 describe 100–300 mcg per administration. Descriptive only, not a recommendation.
A TGF-β-family protein; circulating half-life is not well characterized in humans, so read as approximate.
Growth differentiation factor 11, a TGF-β-family protein studied in heterochronic-parabiosis and rejuvenation models; the findings are preclinical and contested, and no human study fixes an amount or schedule, so no schedule table is shown.
Modelled level — every day
1× is the peak after a single dose.
- Steady-state peak
- 1.00× single dose
- Time to steady state
- 5hours
- Administrations
- 7/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- GDF-11 parabiosis literature (Loffredo FS et al., Cell 2013; Egerman MA et al., Cell Metab 2015)Rodent rejuvenation findings that later reports disputed; human dosing is not established.